Staring as a medical device or a mechanism

Staring at my grandmother, the cutest and kindest person in the world, I was not only
shocked but also in awe. My mind was filled with complicated feelings because of her, wearing
the oxygen mask at that time, and the intricate machines that I do not recognize placed besides
her. At this moment, the machines seemed not only scary but also magical to me as they
allowed my grandmother to keep breathing.
In the first semester at Georgia Institute of Technology, I was considering switching
major from Biomedical Engineering to Industrial and Systems Engineering. Hearing from my
cousin who majored in Industrial and Systems Engineering, I learned that it is a major that
combines business and engineering aspects. I developed an interest in business as an intern at
Gau Jing Machinery Industrial Co., LTD. in the summer of 2014 in Taichuang, Taiwan and
continued to get involved with the industry even after coming back to the U.S. by being one of
their translators when they came for business events. However, I knew I still possessed an
admiration in everything related to biology since high school. It was in the March of 2015, after
my grandmother’s death, that I realized that I was done with the large amount of soul
searching. I finally discovered that my interest lied not in industrial engineering, but in exploring
and designing a solution for a patient, such as a medical device or a mechanism in cell
processing that could have reduced my grandmother’s pain.
Biomedical engineering is a major that incorporates the use of human factors
engineering along with scientific methods to provide patients with the most promising and
comfortable environment. I want to have a career with the flexibility to be in the dynamic world
involving interdisciplinary projects and solving problems on a grand perspective. In addition, I
want to have an opportunity to observe a process of a single mechanism becoming a significant
life-saving strategy or system. To achieve this, I believe a solid foundation in biological system,
human factors, quantitative training infused with hands-on experiences with real world
problems are indispensable.
My undergraduate training and experiences, I believe, have prepared me to face the
rigor and challenges of Ph.D. program. Even though I was overwhelmed by the biomedical
engineering program and was not ready for the pace and difficulties in some courses, I
cogitated and reconsidered my career path after consulting many professionals and decided to
continue my fundamental path from here. I only felt more confident about my choice through
the courses I took in the biomedical engineering department. Many of the fundamentals, both
in biology and engineering aspects, were introduced to me. From the way the program was
designed, I was familiarized with teamwork through numerous projects and presentations. The
projects provided me with the opportunities to interact with different professionals who gave
me the insights to persisting difficulties that ranged from complicated influence of human
factors on certain diseases or disorders to analyzing methods and potential outcomes. The
problems were frustrating but fascinating to me.
Despite this, there were more specialized and sophisticated divisions of professionals in
modern society. I found myself lacking in more in-depth knowledge of many areas as I started
working in the Gaucher Lab. I started off working in the lab as a student assistant and then as
an undergraduate researcher. From my time working as a student assistant, I learned many
fundamental skills that served to prepare me in doing experiments and research later, such as
performing DNA transformation and protein purification, as well as making protein and DNA
gels. As an undergraduate researcher, I have been working on the project of monitoring nanoparticle formation. I am familiar with using advanced instrumentations, NanoTemper
Scattering and Dynamic Light Scattering for example, to assess size, aggregation, and stability of
a nanoparticle of protein uricase. The particle aggregation was confirmed by using NanoTemper
machine, expressing a large increase of particle scattering in many of the samples. We managed
to control the nanoparticle to a size between 50 nm to 300 nm at a concentration of
0.02mg/mL after manipulating the experiments many times.
By learning how to maintain lab sanitation and doing research in nanoparticle, I realized
the gaps between realities and expectations. Doing research on a topic is like exploring an
umbrella term, and there are many more things under that umbrella. The only way to possibly
understand all the ideas and topics under that umbrella is to continue my studies in Yale
University’s graduate program, where I can fulfill the gaps by taking a wide variety of courses
that both deepen my analytical skills and allow the broadening of my knowledge. I believe that
only the incomparable depth of your program would help allow me to become a successful
biomedical engineer.